^No.

^Name

^{Cas No.}

^Abemaciclib 

¹

^{5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinamine}

^1180132-17-5

²

^{6-Bromo-4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazole}

^1231930-33-8

³

^{6-(2-Chloro-5-fluoro-4-pyrimidinyl)-4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazole}

^1231930-42-9

⁴

^Abemaciclib 

^1231929-97-7

⁵

^{Abemaciclib mesylate}

^1231930-82-7

^Brigatinib

¹

^{[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine}

^761440-75-9

²

^{1-(1-(3-Methoxy-4-nitrophenyl)piperidin-4-yl)-4-Methylpiperazine}

^761440-65-7

³

^{2-(diMethylphosphoryl)benzenaMine}

^1197953-47-1

⁴

^{(2-((2,5-dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide}

^1197953-49-3

⁵

^Brigatinib 

^1197953-54-0

^Alectinib

¹

^{2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid}

^1256584-73-2

²

^{tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate}

^1256584-75-4

³

^{4-(Piperidin-4-yl)morpholine}

^53617-35-9

⁴

^{6-Cyano-2-[1-[4-ethyl-3-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-1-methylethyl]-1H-indole-3-carboxylic acid 1,1-dimethylethyl ester} 

^1256698-41-5

⁵

^{6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid}

^1256584-78-7

⁶

^{9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile hydrochloride (1:1)}

^1256589-74-8

⁷

^{9-Ethyl-6,6-dimethyl-8-iodo-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile}

^1256584-80-1

⁸

^Alectinib

^1256580-46-7

^Ceritinib

¹

^{2,5-Dichloro-N-[2-[(1-methylethyl)sulfonyl]phenyl]-4-pyrimidinamine}

 ^761440-16-8

²

^{5-Methyl-2-(1-methylethoxy)-4-(4-piperidinyl)benzenamine hydrochloride (1:2)}

^1380575-45-0

³

^{2-Isopropoxy-5-methyl-4-(piperidin-4-yl)aniline}

^1035230-24-0

⁴

^{1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene}

^1032903-50-6

⁵

^Ceritinib

^1032900-25-6

^AZD-9291

¹

^{N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine} 

 ^1421372-66-8 

²

^{N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-2-nitro-1,4-benzenediamine} 

 ^1421372-67-9  

³

^{N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine} 

^1421372-94-2

⁴

^{4-Fluoro-2-methoxy-5-nitroaniline} 

^1075705-01-9

⁵

^{3-(2-Chloro-4-pyrimidinyl)-1-methyl-1H-indole} 

^1032452-86-0

⁶

^AZD-9291

^1421373-65-0

^Ribociclib

¹

^{2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol}

^1374639-77-6

²

^{3-(2-Chloro-4-cyclopentylamino-pyrimidin-5-yl)-prop-2-yn-1-ol}

^1374639-76-5

³

^{4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester}

 ^571188-59-5 

⁴

^{2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide}

^1211443-61-6

⁵

^{Ribociclib succinate}

^1374639-75-4

^Lenvatinib

¹

^{4-Chloro-7-methoxyquinoline-6-carboxamide} 

^417721-36-9

²

^{4-Amino-3-chlorophenol hydrochloride}

^52671-64-4

³

^{N-(2-Chloro-4-hydroxyphenyl)-N'-cyclopropyl-urea}

^796848-79-8

⁴

^{1,4-Dihydro-7-methoxy-4-oxo-6-quinolinecarboxylic acid methyl ester}

^205448-65-3

⁵

^{4-Amino-3-chlorophenol}

^17609-80-2

⁶

^Lenvatinib

 ^417716-92-8 

^Palbociclib 

¹

^{Ethyl-4-chloro-2-methylthio-5-pyrimidine-carboxylate}

^5909-24-0

²

^{Tert. butyl-4-(6-Nitropyridin-3-yl)piperazino-1-carboxylate}

^571189-16-7

³

^{4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester} 

^571188-59-5

⁴

^{2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d)pyrimidin-7 (8H)-one}

^1013916-37-4

⁵

^{6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one}

^1016636-76-2 

⁶

^palbociclib

^571190-30-2

^Raltitrexed

¹

^{6-Bromomethyl-3,4-dihydro-2-methyl-quinazolin-4-one}

^112888-43-4

²

^{(S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate}

^112889-02-8

³

^Raltitrexed

^112887-68-0

^Crizotinib  

¹

^{(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine} 

^877399-00-3

²

^{Tert-Butyl 4-(4-bromo-1H-pyrazol-1-yl)piperidine-1-carboxylate}

^877399-50-3

³

^{(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol}

^877397-65-4

⁴

^Crizotinib

^877399-52-5

^{Acalabrutinib}

¹

^{2-butynoic acid} 

 ^590-93-2

²

^{2-Chloro-3-cyanopyrazine}

^55557-52-3

³

^{3-Chloro-2-pyrazinemethanamine hydrochloride}

^939412-86-9

⁴

^{4-[8-Amino-3-(2S)-2-pyrrolidinylimidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinylbenzamide}

^1420478-90-5

⁵

^{Acalabrutinib}

^1420477-60-6

^Venetoclax

¹

^{5-bromo-7-azaindole}

^183208-35-7

²

^{3,3-Dimethylcyclohexanone} 

 ^2979-19-3

³

^{1H-pyrrolo[2,3-b]pyridin-5-ol}

^98549-88-3

⁴

^{1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-
en-1-yl]methyl}piperazine}

^1228780-72-0

⁵

^{methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate}

^1235865-75-4

⁶

^{3-nitro-4-[(tetrahydro-2H-pyran-4-
ylmethyl)amino]benzenesulfonamide}

^1228779-96-1

⁷

^{1-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]piperazine dihydrochloride} 

^1628047-87-9

⁸

^Venetoclax

^1257044-40-8

^Ibrutinib 

¹

^{3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine}

^330786-24-8

²

^{(R)-1-Boc-3-hydroxypiperidine}

^143900-43-0

³

^{(S)-1-Boc-3-hydroxypiperidine}

^143900-44-1

⁴

^Ibrutinib

^936563-96-1

^Afatinib 

¹

^{7-Fluoro-6-nitro-4-hydroxyquinazoline}

^162012-69-3

²

^{N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine}

^162012-67-1

³

^{N-(3-Chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4-quinazolinamine}

^314771-88-5

⁴

^{N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine}

^314771-76-1

⁵

^{(S)-(+)-3-Hydroxytetrahydrofuran}

^86087-23-2

⁶

^{Afatinib dimaleate}

^850140-73-7

^Sorafenib

¹

^{4-Chloro-3-(trifluoromethyl)phenyl isocyanate}

^327-78-6

²

^{4-(4-Aminophenoxy)-N-methylpicolinamide} 

^284462-37-9

³

^{N-Methyl-4-chloropyridine-2-carboxamide}

^220000-87-3

⁴

^{Sorafenib tosylate}

^475207-59-1

⁵

^Sorafenib

^284461-73-0

^Nilotinib

¹

^{4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid}

^641569-94-0

²

^{3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline}

^641571-11-1

³

^{Nilotinib hydrochloride monohydrate}

^923288-90-8

^Erlotinib  

¹

^{Ethyl 3,4-dihydroxybenzoate}

^3943-89-3

²

^{Ethyl 4,5-bis(2-methoxyethoxy)-2-aminobenzoate} 

^179688-27-8

³

^{Ethyl 4,5-bis(2-methoxyethoxy)-2-aminobenzoate hydrochloride} 

^183322-17-0

⁴

^{6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone} 

^179688-29-0

⁵

^{4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline}

^183322-18-1

⁶

^{3-Aminophenylacetylene;3-Ethynylaniline}

^54060-30-9  

⁷

^{Erlotinib hydrochloride}

^183319-69-9

^{Irinotecan hydrochloride} 

¹

^Camptothecin 

^86639-63-6

²

^{10-Hydroxycamptothecin}  

^19685-09-7

³

^{7-Ethyl-10-Hydroxy camptothecin}

^86639-52-3

⁴

^{Irinotecan hydrochloride Trihydrate}

^136572-09-3

^Olaparib

¹

^{2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid}

^763114-26-7

²

^{3-cyano-4-fluorobenzaldehyde}

^218301-22-5

³

^{2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile}

^763114-25-6

⁴

^{2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzonitrile}

^1021298-68-9

⁵

^{tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoyl)piperazine-1-carboxylate}

^763114-04-1

⁶

^{2-fluoro-5-formylbenzoic acid}

^550363-85-4

⁷

^{1-(Cyclopropylcarbonyl)piperazine HCl}

^1021298-67-8

^Enzalutamide

¹

^{4-cyano-3-trifluoromethylphenylisothiocyanate}

^143782-23-4

²

^{4-bromo-2-fluoro-N-methylbenzamide}

^749927-69-3

³

^{2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-
2-methylpropanoic acid}

^1289942-66-0

⁴

^{methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate}

^1332524-01-2

⁵

^{4-amino-2-fluoro-N-methylbenzamide}

^915087-25-1

⁶

^Enzalutamide

^915087-33-1

^Apalutamide

¹

^{5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile}

^573762-62-6

²

^{4-amino-2-fluoro-N-methylbenzamide}

^915087-25-1

³

^{4-[(1-Cyanocyclobutyl)amino]-2-fluoro-N-methylbenzamide}

^915087-26-2

⁴

^{4-[7-[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide}

^956104-40-8

⁵

^{5-Isothiocyanato-3-(trifluoromethyl)-2-pyridinecarbonitrile} 

^951753-87-0

^{Larotrectinib} 

¹

^{5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine}

^1363380-51-1

²

^{(R)-2-(2,5-difluorophenyl)pyrrolidine} 

^1919868-77-1

³

^{(R)-2-(2,5-Difluorophenyl)pyrrolidene hydrochloride}

^1218935-60-4

⁴

^{(S)-3-Hydroxypyrrolidine} 

^100243-39-8

⁵

^{(S)-3-Hydroxypyrrolidine hydrochloride} 

^122536-94-1

⁶

^{(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine}

^1223404-90-7

⁷

^{5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-amine}

^1223404-88-3

⁸

^{Larotrectinib sulfate}

^1223405-08-0

^Encorafenib

¹

^{2-Chloro-4-[3-iodo-1-(1-methylethyl)-1H-pyrazol-4-yl]pyrimidine}

^1269440-58-5

²

^{N-[(1S)-2-[[4-[3-Iodo-1-(1-methylethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]amino]-1-methylethyl]carbamic acid methyl ester}

^1269440-60-9

³

^{N-[5-Chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamic acid 1,1-dimethylethyl ester}

^1269440-69-8

⁴

^{N-[(1S)-2-Amino-1-methylethyl]-carbamic acid methyl ester hydrochloride}

^1229025-32-4

⁵

^Encorafenib

^1269440-17-6

^Binimetinib

¹

^{2,3,4-trifluorobenzoic acid}

^61079-72-9

²

^{4-Amino-2,3-difluoro-5-nitrobenzoic acid}

^284030-57-5

³

^{Methyl 4-amino-2,3-difluoro-5-nitrobenzoate}

^284030-58-6

⁴

^{methyl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate}

^1415559-93-1

⁵

^Binimetinib

^606143-89-9

^Vemurafenib

¹

^{2,6-difluoro-3-(propylsulfonamido)benzoic acid}

^1103234-56-5

²

^{5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine}

^918516-27-5