Anti-Hair loss market status

In recent years, the problem of hair loss has increasingly become a major issue that plagues young people, and finding a good cure for hair loss has become a hot topic.
Among the many types of hair loss, androgenetic alopecia (AGA) is a common hair loss symptom characterized by non-scarring shrinkage of hair follicles, widely distributed in susceptible men and women, and is common One of the types of hair loss.
The mechanism of androgenetic alopecia is currently considered to be closely related to genetic predisposition and hormone status. The hormone testosterone (testosterone) in the body will be metabolized into dihydrotestosterone (dihydrotestosterone) under the action of 5α-reductase, and dihydrotestosterone will induce hair follicle hair loss. Shrinking, transforming the terminal hairs into fuzz, which can lead to hair loss if not promptly treated with treatment.
Hair loss usually begins at the frontal hairline with progressive atrophy of the bitemporal hairline, followed by diffuse hair thinning at the apex of the hairline and eventually complete loss of hair in the center of the hairline.
According to literature statistics, among the elderly over 80 years old, about 73% of men and 57% of women will experience androgenetic alopecia, and 58% of men over 50 will suffer from androgenetic alopecia.
The incidence of androgenetic alopecia has racial differences, 80% of white men and 40-50% of white women are affected by androgenetic alopecia; the prevalence of androgenetic alopecia in my country is slightly lower, and the prevalence rate of males is 21.3 %, the female prevalence rate is 6.0%, but due to the large population base, there are not a few people affected by androgenetic alopecia.
The treatment methods for androgenetic alopecia are very limited. At present, there are mainly drug treatment, surgical hair transplantation, laser treatment, etc., and a combination of various methods is often used to delay the progress of androgenetic alopecia symptoms, but the overall solution is not simple. , Satisfactory treatment goals.
Currently, only two drugs, Minoxidil and Finasteride, have been approved by the US FDA for the treatment of androgenetic alopecia. .
Minoxidil (Minoxidil) is a peripheral vasodilator, commonly used in two concentrations of 2% and 5%, when used locally, it can increase the blood flow of blood vessels near the hair follicles and increase the production of vascular endothelial growth factor (VEGF). expression levels, stimulating hair growth in patients.
According to the data of the State Drug Administration, there are currently 8 domestic companies with approval numbers for minoxidil-related dosage forms.
The applicable types of finasteride are more complicated, some high-dose products are suitable for benign prostatic hyperplasia with existing symptoms, while some low-dose products are suitable for the treatment of male androgenetic alopecia.
Finasteride is an inhibitor of type 2 5α-reductase, which can reduce the conversion of testosterone to dihydrotestosterone, thereby slowing down the process of hair follicle shrinkage and hair loss.
A combination of two drugs is often used for male androgenetic alopecia. It has been reported in the literature that after 6 months of treatment of male androgenetic alopecia with finasteride combined with minoxidil liniment, the effective rate can reach 41.67%.
Summary
With the development of the economy, the continuous improvement of living standards, the continuous increase of work pressure, and people's increasing emphasis on their appearance, "baldness" has become a "top priority" for all age groups.
Whether it is drug therapy, combination therapy, or stem cell therapy, the anti-hair loss market has become one of the fastest growing markets at home and abroad. We look forward to a good way to completely treat hair loss and save hair loss stars in the future.